Virologic Efficacy of Boosted Double vs. Boosted Single Protease Inhibitor Therapy
نویسندگان
چکیده
منابع مشابه
Virologic efficacy of boosted double versus boosted single protease inhibitor therapy.
OBJECTIVE Although regimens containing two protease inhibitor (PI) together with ritonavir boosting are used with the aim of improving virologic response to salvage therapy, there is little evidence to support or reject this approach. We compared the probability of attaining an undetectable HIV RNA level after using either boosted double or boosted single PI regimens. DESIGN Retrospective cli...
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BACKGROUND Limited data exist for the efficacy of second-line antiretroviral therapy among children in resource limited settings. We assessed the virologic response to protease inhibitor-based ART after failing first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. METHODS A retrospective chart review was conducted at 8 Thai sites of children who switched to PI -bas...
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PURPOSE A comprehensive study comparing the costs and efficacies of darunavir/ritonavir 800/100 mg qd and the other ritonavir-boosted (/r) protease inhibitors (PIs) recommended for treatment-naïve individuals with HIV-1 infection would help health care decision makers identify the value of each boosted PI. METHODS A cost-efficacy model was developed to compare the five recommended boosted PIs...
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